Cells are defined by the genes they express. In human cells, there are thousands of different protein coding genes, and the expression of those genes is carefully orchestrated and controlled by a ...

Dialing up gene expression Synthetic gene circuits are engineered to include not only the gene of interest, but also a promoter region. At this site, transcription factors and other regulators can ...

It could be simply to control gene expression." The study, "Global impact of unproductive splicing on human gene expression levels and traits," was supported by funding from the National Institutes of ...

What if you could flip a genetic switch to silence a gene, then turn it back on with a simple drug? For researchers, gene-switch tools offer that kind of control—and a new system called Cyclone may ...